Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ammonium phosphate buffer | not below 0.2 mM | Rattus norvegicus | |
Endogenous heat-stable inhibitor | - |
Rattus norvegicus | |
Inositol 1,3,4,5,6-pentakisphosphate | 0.001 mM, 50% inhibition; competitive; strong, kinetics | Rattus norvegicus | |
inositol 1,3,4-trisphosphate | 0.05 mM, about 50% inhibition | Rattus norvegicus | |
Inositol 1,4,5-trisphosphate | 0.05 mM, about 50% inhibition | Rattus norvegicus | |
inositol 3,4,5,6-tetrakisphosphate | 0.01 mM, 40% inhibition | Rattus norvegicus | |
Inositol hexakisphosphate | mixed inhibitor, 0.001 mM, 85% inhibition; more effective than inositol pentakisphosphate; strong, kinetics | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetic data of the cytosolic enzyme | Rattus norvegicus | |
0.007 | 0.008 | D-myo-Inositol 1,3,4,5-tetrakisphosphate | pH 7.2, 37°C, cytosolic enzyme | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
particle-bound | - |
Rattus norvegicus | - |
- |
soluble | - |
Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | Mg2+-dependent | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | inositol 1,3,4,5-tetrakisphosphate 3-phosphatase is unlikely to be an important activity in vivo | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
parotid gland | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O | - |
Rattus norvegicus | D-myo-inositol 1,4,5-trisphosphate + phosphate | - |
? | |
additional information | inositol 1,3,4,5-tetrakisphosphate 3-phosphatase is unlikely to be an important activity in vivo | Rattus norvegicus | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
assay at | Rattus norvegicus |