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Literature summary for 3.1.3.6 extracted from

  • Gbenle, G.O.
    Characterization of a filtrable 3'-nucleotidase of Leishmania donovani (1993), Biochim. Biophys. Acta, 1203, 162-167.
    View publication on PubMed
Search for more literature for 3.1.3.6

Inhibitors

Inhibitors Comment Organism Structure
2'-deoxyadenosine 3'-phosphate
-
 Leishmania donovani
5'-AMP
-
 Leishmania donovani
ADP
-
 Leishmania donovani
ATP
-
 Leishmania donovani
EDTA
-
 Leishmania donovani
p-hydroxymercuribenzoate
-
 Leishmania donovani
Sodium citrate
-
 Leishmania donovani

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.32
-
 3'-AMP
-
 Leishmania donovani

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane 55% on the outer surface and the remaining activity presumably on the inside of the plasma membrane Leishmania donovani 5886
-

Organism

Organism UniProt Comment Textmining
Leishmania donovani
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Leishmania donovani

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-AMP + H2O 92% of the activity with 3'-IMP Leishmania donovani adenosine + phosphate
-
 ?
3'-CMP + H2O 8% of the activity with 3'-IMP Leishmania donovani cytosine + phosphate
-
 ?
3'-GMP + H2O 24% of the activity with 3'-IMP Leishmania donovani guanosine + phosphate
-
 ?
3'-IMP + H2O best substrate Leishmania donovani inosine + phosphate
-
 ?
3'-UMP + H2O 59% of the activity with 3'-IMP Leishmania donovani uridine + phosphate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 activity of the inside of the plasma membrane Leishmania donovani