Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | surface membrane | Leishmania mexicana | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | the enzyme contains a metal cofactor Zn2+-binding domain | Leishmania mexicana |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
41670 | - |
x * 41670, calculation from nucleotide sequence | Leishmania mexicana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Leishmania mexicana | the enzyme plays a critical role in purine salvage pathway during the rapid multiplicative expansion of the parasite population within its insect vector. Starvation of the parasite for purines results in the significant up-regulation of both the 3'-nucleotidase/nuclease mRNA and enzyme activity in promastigotes, but not in amastigotes | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Leishmania mexicana | Q9GNZ4 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
promastigote | stage-specific enzyme, being expressed by promastigote forms, but not by amastigotes | Leishmania mexicana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-AMP + H2O | - |
Leishmania mexicana | adenosine + phosphate | - |
? | |
additional information | the enzyme plays a critical role in purine salvage pathway during the rapid multiplicative expansion of the parasite population within its insect vector. Starvation of the parasite for purines results in the significant up-regulation of both the 3'-nucleotidase/nuclease mRNA and enzyme activity in promastigotes, but not in amastigotes | Leishmania mexicana | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 41670, calculation from nucleotide sequence | Leishmania mexicana |
Synonyms | Comment | Organism |
---|---|---|
3'-nucleotidase/nuclease | - |
Leishmania mexicana |