Literature summary for 3.1.3.56 extracted from

Seow, W.J.; Pan, W.C.; Kile, M.L.; Tong, L.; Baccarelli, A.A.; Quamruzzaman, Q.; Rahman, M.; Mostofa, G.; Rakibuz-Zaman, M.; Kibriya, M.; Ahsan, H.; Lin, X.; Christiani, D.C.
A distinct and replicable variant of the squamous cell carcinoma gene inositol polyphosphate-5-phosphatase modifies the susceptibility of arsenic-associated skin lesions in Bangladesh (2015), Cancer, 121, 2222-2229.

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Application

Application	Comment	Organism
medicine	genetic variation in INPP5A appears to have a role in susceptibility to arsenic toxicity. A single nucleotide polymorphism in the INPP5A gene (rs1133400) shows a significant gene-environment interaction with water arsenic on skin lesion risk	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q14642	-	-

Synonyms

Synonyms	Comment	Organism
INPP5A	-	Homo sapiens

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Release 2026.1 (March 2026)