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Literature summary for 3.1.3.56 extracted from

  • Gunesekera, B.; Torabinejad, J.; Robinson, J.; Gillaspy, G.E.
    Inositol polyphosphate 5-phosphatases 1 and 2 are required for regulating seedling growth (2007), Plant Physiol., 143, 1408-1417.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
molecular biology At5PTase1 and At5PTase2 genes have nonredundant roles in hydrolyzing inositol second-messenger substrates and regulation of Ins(1,4,5)P3 levels is important during germination and early seedling development Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information T-DNA insertional mutants for 5PTase1 (5ptase1-1 and 5ptase1-2, containing a T-DNA insertion within the fifth and fourth introns) and 5PTase2 (5ptase2-1 which contains a T-DNA insertion in the seventh intron) are identified and characterized and a At5PTase1-1/At5PTase2-1 double mutant is produced: grown in dark, seeds from mutants germinate faster than wild-type seeds and the mutant seedlings have longer hypocotyls than wild-type seedlings. Seeds from these mutant lines demonstrate an increase in sensitivity to abscisic acid. These changes in early seedling growth are accompanied by mass increases in Ins(1,4,5)P3, but not by changes in endogenous ABA content. By labeling the endogenous myoinositol pool in 5ptase1 and 5ptase2 mutants, an increases in Ins(1,4,5)P3 and a decrease in PtdIns, PtdIns(4)P, and phosphatidylinositol (4,5)bisphosphate is detected Arabidopsis thaliana
additional information T-DNA insertional mutants for 5PTase1 (5ptase1-1 and 5ptase1-2, containing a T-DNA insertion within the fifth and fourth introns) and 5PTase2 (5ptase2-1 which contains a T-DNA insertion in the seventh intron) are identified and characterized and a At5PTase1-1/At5PTase2-1 double mutant is produced: grown in dark, seeds from mutants germinate faster than wildtype seeds and the mutant seedlings have longer hypocotyls than wild-type seedlings. Seeds from these mutant lines demonstrate an increase in sensitivity to abscisic acid. These changes in early seedling growth are accompanied by mass increases in Ins(1,4,5)P3, but not by changes in endogenous ABA content. By labeling the endogenous myoinositol pool in 5ptase1 and 5ptase2 mutants, an increases in Ins(1,4,5)P3 and a decrease in PtdIns, PtdIns(4)P, and phosphatidylinositol (4,5)bisphosphate is detected Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q84MA2
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Arabidopsis thaliana Q9FUR2
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Source Tissue

Source Tissue Comment Organism Textmining
flower
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Arabidopsis thaliana
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leaf rosette leaves, cauline leaves Arabidopsis thaliana
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additional information expression of At5pTase1 is weaker than At5Ptase2 Arabidopsis thaliana
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additional information expression of At5pTase2 is generally stronger than At5Ptase1 Arabidopsis thaliana
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root
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Arabidopsis thaliana
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seedling
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Arabidopsis thaliana
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Synonyms

Synonyms Comment Organism
5PTase1
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Arabidopsis thaliana
5PTase2
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Arabidopsis thaliana
At5pTase1
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Arabidopsis thaliana
At5pTase2
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Arabidopsis thaliana
inositol polyphosphate 5-phosphatases 1
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Arabidopsis thaliana