| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2,3-bisphosphoglycerate | - |
Homo sapiens | |
| N-ethylmaleimide | - |
Homo sapiens | |
| Phenylglyoxal | Arg-343 and Arg-350 were found to be covalently modified; irreversible, substrates and 2,3-bisphosphoglycerate protect against inactivation | Homo sapiens |
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | membrane associated enzyme has lower specific activity than soluble enzyme | Homo sapiens | 16020 | - |
| soluble | - |
Homo sapiens | - |
- |
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Homo sapiens |
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O | Homo sapiens | - |
D-myo-inositol 1,3,4-trisphosphate + phosphate | - |
? | |
| D-myo-inositol 1,4,5-trisphosphate + H2O | Homo sapiens | regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate | D-myo-inositol 1,4-bisphosphate + phosphate | - |
? |
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| side-chain modification | isoprenylation | Homo sapiens |
| side-chain modification | farnesylation | Homo sapiens |
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Homo sapiens | - |
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O | - |
Homo sapiens | D-myo-inositol 1,3,4-trisphosphate + phosphate | - |
? | |
| D-myo-inositol 1,4,5-trisphosphate + H2O | - |
Homo sapiens | D-myo-inositol 1,4-bisphosphate + phosphate | - |
? | |
| D-myo-inositol 1,4,5-trisphosphate + H2O | regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate | Homo sapiens | D-myo-inositol 1,4-bisphosphate + phosphate | - |
? |