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Literature summary for 3.1.3.56 extracted from

  • Lynch, B.J.; Challiss, R.A.J.; Chilvers, E.R.
    Characterisation and Ca(2+)-dependency of the soluble and particulate Ins(1,4,5)P3 5-phosphatase in bovine tracheal smooth muscle (1994), Biochem. Soc. Trans., 22, 314S.
    View publication on PubMed
Search for more literature for 3.1.3.56

Inhibitors

Inhibitors Comment Organism Structure
Ca2+ above 0.001 mM Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.018
-
 D-myo-inositol 1,4,5-trisphosphate particulate enzyme Bos taurus
0.019
-
 D-myo-inositol 1,4,5-trisphosphate soluble enzyme Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane 5 times higher Vmax than soluble enzyme Bos taurus 16020
-
soluble
-
 Bos taurus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ moderate inhibition Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-myo-inositol 1,4,5-trisphosphate + H2O Bos taurus regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
muscle tracheal smooth muscle Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-myo-inositol 1,4,5-trisphosphate + H2O
-
 Bos taurus D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?
D-myo-inositol 1,4,5-trisphosphate + H2O regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate Bos taurus D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?