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Literature summary for 3.1.3.53 extracted from

  • Lartey, J.; Taggart, J.; Robson, S.; Taggart, M.
    Altered expression of human smooth muscle myosin phosphatase targeting (MYPT) isovariants with pregnancy and labor (2016), PLoS ONE, 11, e0164352 .
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
medicine the expression of isovariants PPP1R12A, PPP1R12BLZ+, PPP1R16A and PPP1R16B mRNA is reduced in late pregnancy (not-in-labor) relative to non-pregnancy. PPP1R12ALZ+ and PPP1R12ALZ- mRNA levels are similar in the non-pregnant and pregnant not-in-labor groups. There is a further reduction in the uterine expression of PPP1R12ALZ+, PPP1R12CLZ+ and PPP1R12ALZ- mRNA with labor relative to the pregnant not-in-labor group. PPP1R12A, PPP1R12BLZ+, PPP1R16A and PPP1R16B mRNA levels are invariant between the not in labor and in-labor groups Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O14974
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-

Source Tissue

Source Tissue Comment Organism Textmining
smooth muscle
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 Homo sapiens
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Expression

Organism Comment Expression
Homo sapiens the expression of isovariants PPP1R12A, PPP1R12BLZ+, PPP1R16A and PPP1R16B mRNA is reduced in late pregnancy (not-in-labor) relative to non-pregnancy. PPP1R12ALZ+ and PPP1R12ALZ- mRNA levels are similar in the non-pregnant and pregnant not-in-labor groups. There is a further reduction in the uterine expression of PPP1R12ALZ+, PPP1R12CLZ+ and PPP1R12ALZ- mRNA with labor relative to the pregnant not-in-labor group. PPP1R12A, PPP1R12BLZ+, PPP1R16A and PPP1R16B mRNA levels are invariant between the not in labor and in-labor groups additional information