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Literature summary for 3.1.3.53 extracted from

  • Jayashankar, V.; Nguyen, M.J.; Carr, B.W.; Zheng, D.C.; Rosales, J.B.; Rosales, J.B.; Weiser, D.C.
    Protein phosphatase 1 beta paralogs encode the zebrafish myosin phosphatase catalytic subunit (2013), PLoS ONE, 8, e75766.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
subunits are expressed as a GST-fusion protein in Escherichia coli Danio rerio

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Danio rerio both gene products of protein phosphatase 1, PP1, (catalytic subunit of the myosin phosphatase) ppp1cba and ppp1cbb interact with Mypt1 (regulatory subunit of the myosin phosphatase) and assemble an active myosin phosphatase complex ?
-
?

Organism

Organism UniProt Comment Textmining
Danio rerio
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information both gene products of protein phosphatase 1, PP1, (catalytic subunit of the myosin phosphatase) ppp1cba and ppp1cbb interact with Mypt1 (regulatory subunit of the myosin phosphatase) and assemble an active myosin phosphatase complex Danio rerio ?
-
?
myosin light-chain phosphate + H2O
-
Danio rerio myosin light-chain + phosphate
-
?

Synonyms

Synonyms Comment Organism
myosin phosphatase
-
Danio rerio

General Information

General Information Comment Organism
malfunction Morpholino knock-down of ppp1cba and ppp1cbb results in severe defects in morphogenetic cell movements during gastrulation through loss of myosin phosphatase function Danio rerio