Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-amino-4-bromo-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid | - |
Homo sapiens | |
1-amino-4-bromo-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid | - |
Rattus norvegicus | |
4-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonic acid | compound shows high cytotoxicity on H157 cells, with about 72% at 100 mM final concentration | Homo sapiens | |
4-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonic acid | - |
Rattus norvegicus | |
6-amino-4-hydroxynaphthalene-2-sulfonic acid | most potent inhibitor of the screen | Homo sapiens | |
6-amino-4-hydroxynaphthalene-2-sulfonic acid | most potent inhibitor of the screen | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
ecto-5'-nucleotidase | - |
Rattus norvegicus | - |
ecto-5'-nucleotidase | - |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00132 | - |
pH 7.4, 37°C | Homo sapiens | 6-amino-4-hydroxynaphthalene-2-sulfonic acid | |
0.004 | - |
pH 7.4, 37°C | Homo sapiens | 1-amino-4-bromo-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid | |
0.0061 | - |
pH 7.4, 37°C | Homo sapiens | 4-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonic acid | |
0.0104 | - |
pH 7.4, 37°C | Rattus norvegicus | 6-amino-4-hydroxynaphthalene-2-sulfonic acid | |
0.027 | - |
pH 7.4, 37°C | Rattus norvegicus | 1-amino-4-bromo-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid | |
0.0443 | - |
pH 7.4, 37°C | Rattus norvegicus | 4-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonic acid |