Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
[a protein]-tyrosine phosphate + H2O | Rattus norvegicus | - |
[a protein]-tyrosine + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | aggregation of the high-affinity IgE receptor FceRI induces the phosphorylation of PTP-PEST at Ser39, thus resulting in the suppression of enzyme activity | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
basophilic leukemia cell | - |
Rattus norvegicus | - |
RBL-2H3 cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[a protein]-tyrosine phosphate + H2O | - |
Rattus norvegicus | [a protein]-tyrosine + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
protein tyrosine phosphatase-PEST | - |
Rattus norvegicus |
PTP-PEST | - |
Rattus norvegicus |
PTPN12 | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | PTP-PEST mRNA expression is significantly induced upon the high-affinity IgE receptor FceRI-crosslinking | up |
General Information | Comment | Organism |
---|---|---|
physiological function | protein tyrosine phosphatase-PEST regulates mast cell-activating signals in protein tyrosine phosphatase activity-dependent and -independent manners | Rattus norvegicus |