Literature summary for 3.1.3.48 extracted from

Evdokimov, A.G.; Pokross, M.; Walter, R.; Mekel, M.; Cox, B.; Li, C.; Bechard, R.; Genbauffe, F.; Andrews, R.; Diven, C.; Howard, B.; Rastogi, V.; Gray, J.; Maier, M.; Peters, K.G.
Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery (2006), Acta Crystallogr. Sect. D, 62, 1435-1445.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
hanging drop vapour diffusion method with 18-22% PEG 8000, 200 mM MgCl2, 100 mM Tris-HCl pH 8.0, and 1% (v/v) beta-mercaptoethanol	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	-	Homo sapiens	5737	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P23467	-	-

Purification (Commentary)

Purification (Comment)	Organism
Q-15 ion-exchange resin chromatography	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
endothelial cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
HPTPbeta-CD	-	Homo sapiens
protein tyrosine phosphatase beta	-	Homo sapiens
PTP1B	-	Homo sapiens
PTPbeta	-	Homo sapiens

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Release 2023.1 (January 2023)