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Literature summary for 3.1.3.46 extracted from

  • Payne, V.A.; Arden, C.; Lange, A.J.; Agius, L.
    Contributions of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2 to the elevated glycolysis in hepatocytes from Zucker fa/fa rats (2007), Am. J. Physiol. Regul. Integr. Comp. Physiol., 293, R618-R625.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in hepatocytes of the wild type enzyme and of the kinase active double mutant S32A/H258A, overexpression of glukokinase and PFK have a synergistic effect on beta-D-fructose 2,6-bisphosphate levels Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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insulin-resistant Zucker fa/fa and Fa/? strains
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Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte cell culture Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-D-fructose 2,6-bisphosphate + H2O
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Rattus norvegicus D-fructose 6-phosphate + phosphate
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?

Synonyms

Synonyms Comment Organism
6-phosphofructo-2-kinase/fructose-2 6-biphosphatase
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Rattus norvegicus
PFK2
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Rattus norvegicus