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Literature summary for 3.1.3.43 extracted from
- Activated function of the pyruvate dehydrogenase phosphatase through Ca2+-facilitated binding to the inner lipoyl domain of the dihydrolipoyl acetyltransferase (1996), J. Biol. Chem., 271, 28064-28070.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EGTA | - |
Bos taurus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Bos taurus | 5739 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | aiding the association of PDP with dihydrolipoyl acetyltransferase | Bos taurus | |
| Mg2+ | - |
Bos taurus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| [pyruvate dehydrogenase (lipoamide)]-phosphate + H2O | Bos taurus | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| [pyruvate dehydrogenase (lipoamide)]-phosphate + H2O | - |
Bos taurus | [pyruvate dehydrogenase (lipoamide)] + phosphate | - |
ir | |
| [pyruvate dehydrogenase (lipoamide)]-phosphate + H2O | - |
Bos taurus | ? | - |
? | |
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Release 2023.1 (January 2023)
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