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Literature summary for 3.1.3.43 extracted from

  • Guo, X.; Niemi, N.; Coon, J.; Pagliarini, D.
    Integrative proteomics and biochemical analyses define Ptc6p as the Saccharomyces cerevisiae pyruvate dehydrogenase phosphatase (2017), J. Biol. Chem., 292, 11751-11759 .
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
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Saccharomyces cerevisiae 5739
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Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[Pda1]-phosphate + H2O enzyme acts on residue S313 of pyruvate dehydrogenase complex E1alpha subunit Pda1 Saccharomyces cerevisiae [Pda1] + phosphate
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?

Synonyms

Synonyms Comment Organism
Ptc6
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Saccharomyces cerevisiae

General Information

General Information Comment Organism
physiological function Ptc6 interacts with pyruvate dehydrogenase complex E1alpha subunit Pda1. A Ptc6 deletion mutant exhibits a marked increase in Pda1 S313 phosphorylation Saccharomyces cerevisiae