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Literature summary for 3.1.3.4 extracted from

  • Hernandez, M.A.; Comba, S.; Arabolaza, A.; Gramajo, H.; Alvarez, H.M.
    Overexpression of a phosphatidic acid phosphatase type 2 leads to an increase in triacylglycerol production in oleaginous Rhodococcus strains (2015), Appl. Microbiol. Biotechnol., 99, 2191-2207.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Rhodococcus jostii

Organism

Organism UniProt Comment Textmining
Rhodococcus jostii Q0SKM5
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-

Synonyms

Synonyms Comment Organism
RHA1_ro00075
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Rhodococcus jostii

General Information

General Information Comment Organism
physiological function conditional deletion of the enzyme gene leads to a decrease in the content of diacylglycerol and triacylglycerol, whereas its overexpression in both Rhodococcus jostii RHA1 and Rhodococcus opacus PD630 promotes an increase up to 10 to 15% by cellular dry weight in triacylglycerol content. Expression in the nonoleaginous strain Rhodococcus fascians F7 promotes an increase in total fatty acid content up to 7% at the expense of free fatty acid, diacylglycerol, and triacylglycerol fractions. Coexpression with Atf2 gene encoding wax ester/diacylglycerol acyltransferase results in a fourfold increase in total fatty acid content by a further increase of the free fatty acid and triacylglycerol fractions Rhodococcus jostii