Activating Compound | Comment | Organism | Structure |
---|---|---|---|
androgen | highly induces LPP1 expression in LNCaP cells | Homo sapiens | |
methyltrienolone | induces LPP1 expression | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
NIH3T3 cells stably expressing LPP1-CFP or LPP3-CFP. MDCK cells stably expressing LPP1-GFP and LPP3-GFP. COS-7 and PC-12 cells transiently expressing LPP1 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | CHAPS-insoluble LPP1 is resistant to the actin-disrupting drug cytochalasin D. CHAPS-resistant floating complexes containing LPP1 are sensitive to cholesterol depletion | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
Golgi apparatus | CHAPS-resistant complexes containing LPP1 | Homo sapiens | 5794 | - |
membrane | LPP1 and LPP3 are distributed in distinct lipid rafts that may provide unique microenvironments defining their non-redundant physiological functions. LPP1 is associated with rafts, which are segregated from those harboring LPP3, in a Triton-100-sensitive but CHAPS-resistant manner | Homo sapiens | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
LNCaP cell | LPP1 | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
lipid phosphate phosphatase 1 | - |
Homo sapiens |
lipid phosphate phosphatase 3 | - |
Homo sapiens |
LPP1 | - |
Homo sapiens |
LPP3 | - |
Homo sapiens |