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Literature summary for 3.1.3.36 extracted from
- Phosphoinositide 5-phosphatases: How do they affect tumourigenesis? (2013), J. Biochem., 153, 1-3.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O | Homo sapiens | - |
1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + phosphate | - |
? |  |
| 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O | Homo sapiens | - |
1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q9NRR6 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O | - |
Homo sapiens | 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + phosphate | - |
? | |
| 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O | - |
Homo sapiens | 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| INPP5E | - |
Homo sapiens |
| Phosphoinositide 5-phosphatase | - |
Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | isoform INPP5E is overexpressed in cervical cancer, non-Hodgkins lymphoma, and uterine leiomyosarcoma | up |
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Release 2023.1 (January 2023)
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