Application | Comment | Organism |
---|---|---|
molecular biology | SHIP2 lipid phosphatase activity plays an important role in the metabolism of PtdIns(3,4,5)P3 in response to H2O2 | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | in SHIP2 deficient mouse embryonic fibroblasts (MEFs) stimulated by H2O2 at 15 min, PtdIns(3,4,5)P3 is increased as compared to +/+ cells. No significant increase in PtdIns(3,4)P2 can be detected at 15 or 120 min incubation of the cells with H2O2 (0.6 mM). PKB activity is also upregulated in SHIP2 -/- cells as compared to +/+ cells in response to H2O2 | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
inositol 5-phosphatase SHIP2 | - |
Mus musculus |
SHIP2 | - |
Mus musculus |