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Literature summary for 3.1.3.36 extracted from

  • Palmer, F.B.S.C.; Theolis, R.; Cook, H.W.; Byers, D.M.
    Purification of two immunologically related phosphatidylinositol-(4,5)-bisphosphate phosphatases from bovine brain cytosol (1994), J. Biol. Chem., 269, 3403-3410.
    View publication on PubMed
Search for more literature for 3.1.3.36

Inhibitors

Inhibitors Comment Organism Structure
2,3-diphosphoglycerate
-
 Bos taurus

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ stimulates with 85-90% of the optimal activity in presence of Mg2+ Bos taurus
Mg2+ required Bos taurus
Mn2+ as effective in stimulation as Mg2+ Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
115000
-
 x * 115000, SDS-PAGE Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Bos taurus

Storage Stability

Storage Stability Organism
-20°C, 0.1 M NaCl, very littly loss of activity after several months Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
myo-inositol 1,4,5-trisphosphate + H2O at 17% of the activity with phosphatidyl-myo-inositol 4,5-bisphosphate Bos taurus inositol 1,4-diphosphate + phosphate
-
 ?
myo-inositol 1,4,5-trisphosphate + H2O at 30% of the activity with phosphatidyl-myo-inositol 4,5-bisphosphate Bos taurus inositol 1,4-diphosphate + phosphate
-
 ?
phosphatidyl-myo-inositol 4,5-bisphosphate + H2O
-
 Bos taurus phosphatidylinositol 4-phosphate + phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 115000, SDS-PAGE Bos taurus