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Literature summary for 3.1.3.32 extracted from

  • Jilani, A.; Ramotar, D.; Slack, C.; Ong, C.; Yang, X.M.; Scherer, S.W.; Lasko, D.D.
    Molecular cloning of the human gene, PNKP, encoding a polynucleotide kinase 3-phosphatase and evidence for its role in repair of DNA strand breaks caused by oxidative damage (1999), J. Biol. Chem., 274, 24176-24186.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
57100
-
 x * 57100, calculation from sequence of cDNA Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phopsho-5'-hydroxy-DNA Homo sapiens role in repair of DNA strand breaks caused by oxidative damage ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q96T60
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phopsho-5'-hydroxy-DNA role in repair of DNA strand breaks caused by oxidative damage Homo sapiens ?
-
 ?
pTp + H2O
-
 Homo sapiens pT + phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 57100, calculation from sequence of cDNA Homo sapiens