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Literature summary for 3.1.3.32 extracted from

  • Shirodkar, P.; Fenton, A.L.; Meng, L.; Koch, C.A.
    Identification and functional characterization of a Ku-binding motif in aprataxin polynucleotide kinase/phosphatase-like factor (APLF) (2013), J. Biol. Chem., 288, 19604-19613.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.3.32

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
 Homo sapiens 5634
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
APLF also known as PALF and Xip1 Homo sapiens
APTX/PNKP-like factor
-
 Homo sapiens
PNKP
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 Homo sapiens
polynucleotide kinase/phosphatase
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 Homo sapiens

General Information

General Information Comment Organism
metabolism aprataxin polynucleotide kinase/phosphatase-like factor (APLF) facilitates nonhomologous end joining (NHEJ) and associates with the core NHEJ components XRCC4-DNA ligase IV and Ku. The APLF-Ku interaction is functionally important in DNA repair and may be important for APLF stability Homo sapiens