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Literature summary for 3.1.3.26 extracted from

  • Iqbal, T.H.; Lewis, K.O.; Cooper, B.T.
    Phytase activity in the human and rat small intestine (1994), Gut, 35, 1233-1236.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.3.26

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens undegraded phytates can cause mineral deficiencies in humans. The presence of undigested phytate in the colon may protect against the development of colonic carcinoma ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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 The enzyme may be a 3-phytase (EC 3.1.3.8), or a 4-phytase (synonym 6-phytase, EC 3.1.3.26). The product of the hydrolysis of myo-inositol hexakisphosphate to 1D-myo-inositol 1,2,4,5,6-pentakisphosphate or alternatively 1D-myo-inositol 1,2,3,5,6-pentakisphosphate has not been identified.
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Rattus norvegicus
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 The enzyme may be a 3-phytase (EC 3.1.3.8), or a 4-phytase (synonym 6-phytase, EC 3.1.3.26). The product of the hydrolysis of myo-inositol hexakisphosphate to 1D-myo-inositol 1,2,4,5,6-pentakisphosphate or alternatively 1D-myo-inositol 1,2,3,5,6-pentakisphosphate has not been identified.
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Source Tissue

Source Tissue Comment Organism Textmining
small intestine activity is greatest in duodenum and lowest in ileum Homo sapiens
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small intestine activity is greatest in duodenum and lowest in ileum Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information undegraded phytates can cause mineral deficiencies in humans. The presence of undigested phytate in the colon may protect against the development of colonic carcinoma Homo sapiens ?
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 ?
myo-inositol hexakisphosphate + H2O
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 Homo sapiens myo-inositol pentakisphosphate + phosphate
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 ?
myo-inositol hexakisphosphate + H2O
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 Rattus norvegicus myo-inositol pentakisphosphate + phosphate
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 ?