BRENDA - Enzyme Database
show all sequences of 3.1.3.23

Sugar phosphate phosphohydrolase. I. Substrate specificity, intracellular localization, and purification from Neisseria meningitidis

Lee, Y.P.; Sowokinos, J.R.; Erwin, M.J.; J. Biol. Chem. 242, 2264-2271 (1967)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasmic membrane
-
Neisseria meningitidis
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Neisseria meningitidis
-
-
-
Purification (Commentary)
Commentary
Organism
-
Neisseria meningitidis
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-Deoxy-D-glucose 6-phosphate + H2O
103% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
2-Deoxy-D-glucose + phosphate
-
-
-
?
alpha-D-galactose 1-phosphate + H2O
115% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
alpha-D-galactose + phosphate
-
-
-
?
alpha-D-gentibiose-1-phosphate + H2O
66% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
alpha-D-gentibiose + phosphate
-
-
-
?
alpha-D-glucose 1-phosphate + H2O
-
94722
Neisseria meningitidis
alpha-D-glucose + phosphate
-
-
-
?
alpha-D-glucuronic acid 1-phosphate + H2O
75.6% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
alpha-D-glucuronic acid + phosphate
-
-
-
?
alpha-D-mannose 1-phosphate + H2O
103% of the activity with alpha-D-mannose 1-phosphate
94722
Neisseria meningitidis
alpha-D-mannose + phosphate
-
-
-
?
alpha-lactose 1-phosphate + H2O
15% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
alpha-lactose + phosphate
-
-
-
?
D-fructose 1,6-diphosphate + H2O
93% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
?
-
-
-
?
D-fructose 1-phosphate + H2O
104% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-fructose + phosphate
-
-
-
?
D-fructose 6-phosphate + H2O
104% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-fructose + phosphate
-
-
-
?
D-galactose 6-phosphate + H2O
30.3% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-galactose + phosphate
-
-
-
?
D-glucose 6-phosphate + H2O
106% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-glucose + phosphate
-
-
-
?
D-glyceraldehyde 3-phosphate + H2O
24.5% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-glyceraldehyde + phosphate
-
-
-
?
D-mannose 6-phosphate + H2O
28.5% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-mannose + phosphate
-
-
-
?
D-ribose 5-phosphate + H2O
24.8% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-ribose + phosphate
-
-
-
?
D-sorbose 1,6-diphosphate + H2O
15% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
?
-
-
-
?
D-sorbose 1-phosphate + H2O
108% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-sorbose + phosphate
-
-
-
?
D-xylose 1-phosphate + H2O
72% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-xylose + phosphate
-
-
-
?
dihydroxyacetone phosphate + H2O
12% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
dihydroxyacetone + phosphate
-
-
-
?
inositol phosphate + H2O
5% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
inositol + phosphate
-
-
-
?
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasmic membrane
-
Neisseria meningitidis
-
-
Purification (Commentary) (protein specific)
Commentary
Organism
-
Neisseria meningitidis
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-Deoxy-D-glucose 6-phosphate + H2O
103% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
2-Deoxy-D-glucose + phosphate
-
-
-
?
alpha-D-galactose 1-phosphate + H2O
115% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
alpha-D-galactose + phosphate
-
-
-
?
alpha-D-gentibiose-1-phosphate + H2O
66% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
alpha-D-gentibiose + phosphate
-
-
-
?
alpha-D-glucose 1-phosphate + H2O
-
94722
Neisseria meningitidis
alpha-D-glucose + phosphate
-
-
-
?
alpha-D-glucuronic acid 1-phosphate + H2O
75.6% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
alpha-D-glucuronic acid + phosphate
-
-
-
?
alpha-D-mannose 1-phosphate + H2O
103% of the activity with alpha-D-mannose 1-phosphate
94722
Neisseria meningitidis
alpha-D-mannose + phosphate
-
-
-
?
alpha-lactose 1-phosphate + H2O
15% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
alpha-lactose + phosphate
-
-
-
?
D-fructose 1,6-diphosphate + H2O
93% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
?
-
-
-
?
D-fructose 1-phosphate + H2O
104% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-fructose + phosphate
-
-
-
?
D-fructose 6-phosphate + H2O
104% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-fructose + phosphate
-
-
-
?
D-galactose 6-phosphate + H2O
30.3% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-galactose + phosphate
-
-
-
?
D-glucose 6-phosphate + H2O
106% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-glucose + phosphate
-
-
-
?
D-glyceraldehyde 3-phosphate + H2O
24.5% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-glyceraldehyde + phosphate
-
-
-
?
D-mannose 6-phosphate + H2O
28.5% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-mannose + phosphate
-
-
-
?
D-ribose 5-phosphate + H2O
24.8% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-ribose + phosphate
-
-
-
?
D-sorbose 1,6-diphosphate + H2O
15% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
?
-
-
-
?
D-sorbose 1-phosphate + H2O
108% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-sorbose + phosphate
-
-
-
?
D-xylose 1-phosphate + H2O
72% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
D-xylose + phosphate
-
-
-
?
dihydroxyacetone phosphate + H2O
12% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
dihydroxyacetone + phosphate
-
-
-
?
inositol phosphate + H2O
5% of the activity with alpha-D-glucose 1-phosphate
94722
Neisseria meningitidis
inositol + phosphate
-
-
-
?
Other publictions for EC 3.1.3.23
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
750977
Zeng
Essential roles of the sppRA ...
Streptococcus mutans
J. Bacteriol.
201
e00586
2019
-
-
1
-
-
-
1
2
-
2
-
-
-
1
-
-
-
-
-
-
-
1
3
1
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
2
-
2
-
-
-
-
-
-
-
-
-
1
3
1
-
-
-
-
1
-
-
-
2
1
1
2
-
-
749666
Maleki
Identification of a new phosp ...
Pseudomonas fluorescens, Pseudomonas fluorescens SBW25
Appl. Environ. Microbiol.
83
e02361
2017
-
-
1
-
-
-
2
2
-
1
-
-
-
5
-
-
-
-
-
-
-
-
8
1
-
-
-
2
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
2
-
1
-
-
-
-
-
-
-
-
-
-
8
1
-
-
-
2
-
-
-
-
-
1
1
-
2
2
730458
Guggisberg
A sugar phosphatase regulates ...
Plasmodium falciparum
Nat. Commun.
5
4467
2014
-
-
1
1
1
-
-
-
1
1
1
1
-
3
-
-
1
-
-
-
-
-
16
1
-
-
-
-
-
-
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-
-
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1
-
1
1
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1
1
1
1
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-
1
-
-
-
-
16
1
-
-
-
-
-
-
-
-
-
2
2
-
-
-
730667
Caparros-Martin
The kinetic analysis of the su ...
Arabidopsis thaliana
Planta
240
479-487
2014
-
-
1
-
5
-
-
22
-
1
1
-
-
2
-
-
1
-
-
-
-
-
8
1
-
-
-
17
1
-
-
-
-
-
-
-
-
1
-
-
5
-
-
-
-
22
-
1
1
-
-
-
-
1
-
-
-
-
8
1
-
-
-
17
1
-
-
-
-
-
-
-
23
23
714982
Godinho
Characterization and regulatio ...
Bacillus subtilis
FEBS J.
278
2511-2524
2011
-
-
1
-
3
-
-
7
-
1
1
1
-
3
-
-
1
-
-
-
-
-
8
1
1
1
-
7
1
1
-
-
-
-
-
-
-
1
-
-
3
-
-
-
-
7
-
1
1
1
-
-
-
1
-
-
-
-
8
1
1
1
-
7
1
1
-
-
-
2
2
-
7
7
94728
Ye
-
Inducer expulsion and the occu ...
Enterococcus faecalis, Streptococcus pyogenes
Microbiology
142
585-592
1996
-
-
-
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
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-
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2
-
-
-
-
-
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-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94725
Cook
Properties of two sugar phosph ...
Streptococcus equinus
J. Bacteriol.
177
7007-7009
1995
1
-
-
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94727
Ye
Purification and characterizat ...
Lactococcus lactis
J. Biol. Chem.
270
16740-16744
1995
1
-
-
-
-
-
-
1
1
5
-
-
-
1
-
-
-
-
-
-
-
-
10
-
-
-
1
-
1
1
-
-
-
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-
1
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-
-
-
-
-
-
-
1
1
5
-
-
-
-
-
-
-
-
-
-
10
-
-
-
1
-
1
1
-
-
-
-
-
-
-
-
94726
Choy
Survey, purification, and prop ...
Escherichia acidilactici, Escherichia coli, Klebsiella aerogenes, Neisseria meningitidis, Saccharomyces cerevisiae
Can. J. Biochem. Cell Biol.
61
1292-1303
1983
-
-
-
-
-
-
-
-
-
-
7
-
-
31
-
-
5
-
-
-
7
-
35
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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7
-
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5
-
-
7
-
35
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
94724
Lau
Effects of fluoride on sugar p ...
Escherichia coli, Neisseria meningitidis
Int. J. Biochem.
14
565-567
1982
-
-
-
-
-
-
2
-
1
-
-
-
-
5
-
-
2
-
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1
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2
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1
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2
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1
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-
-
-
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-
-
-
-
-
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-
94723
Lee
-
Molecular weight and some phys ...
Escherichia coli, Neisseria meningitidis
J. Biol. Chem.
250
3729-3737
1975
-
-
-
1
-
-
11
16
-
-
4
-
-
2
-
-
1
-
-
-
1
1
32
1
-
-
4
-
1
1
3
-
-
-
-
-
-
-
-
1
-
-
-
11
-
16
-
-
4
-
-
-
-
1
-
-
1
1
32
1
-
-
4
-
1
1
3
-
-
-
-
-
-
-
94722
Lee
Sugar phosphate phosphohydrola ...
Neisseria meningitidis
J. Biol. Chem.
242
2264-2271
1967
-
-
-
-
-
-
-
-
3
-
-
-
-
3
-
-
1
-
-
-
-
-
20
-
-
-
-
-
-
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-
-
-
-
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3
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1
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20
-
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