Inhibitors | Comment | Organism | Structure |
---|---|---|---|
okadaic acid | complete inhibition at 250 nM | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
PC-12 cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphorylated tropomyosin-related kinase A + H2O | two neuron-enriched regulatory subunits, B'beta and B'delta, recruit PP2A into a complex with tropomyosin-related kinase A to dephosphorylate the nerve growth factor receptor on Ser/Thr residues and to potentiate its intrinsic tyrosine kinase activity | Rattus norvegicus | tropomyosin-related kinase A + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterotrimer | - |
Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
PP2A | - |
Rattus norvegicus |
protein phosphatase 2A | - |
Rattus norvegicus |