Literature summary for 3.1.3.16 extracted from

Nagase, T.; Murakami, T.; Nozaki, H.; Inoue, R.; Nishito, Y.; Tanabe, O.; Usui, H.; Takeda, M.
Tissue and subcellular distributions, and characterization of rat brain protein phosphatase 2A containing a 72-kDa delta/B subunit (1997), J. Biochem., 122, 178-187.

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Inhibitors

Inhibitors	Comment	Organism	Structure
okadaic acid	-	Rattus norvegicus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0723	-	phosphohistone	-	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	-	Homo sapiens	5737	-
cytoplasm	-	Rattus norvegicus	5737	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
34000	-	phosphatase 2A, 1 * 72000 + 1 * 63000 + 1 * 34000, SDS-PAGE	Homo sapiens
63000	-	phosphatase 2A, 1 * 72000 + 1 * 63000 + 1 * 34000, SDS-PAGE	Homo sapiens
72000	-	phosphatase 2A, 1 * 72000 + 1 * 63000 + 1 * 34000, SDS-PAGE	Homo sapiens
170000	-	phosphatase PP2A, gel filtration	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Rattus norvegicus	-

Storage Stability

Storage Stability	Organism
-80°C, 20 mM Tris-HCl, pH 7.4, 1 mM EDTA, 10% glycerol	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
phosphohistone + H2O	-	Homo sapiens	histone + phosphate	-	?
phosphohistone + H2O	-	Rattus norvegicus	histone + phosphate	-	?
phosphoproteins + H2O	-	Homo sapiens	proteins + phosphate	-	?
phosphoproteins + H2O	-	Rattus norvegicus	proteins + phosphate	-	?

Subunits

Subunits	Comment	Organism
trimer	-	Rattus norvegicus
trimer	phosphatase 2A, 1 * 72000 + 1 * 63000 + 1 * 34000, SDS-PAGE	Homo sapiens

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Release 2023.1 (January 2023)