Activating Compound | Comment | Organism | Structure |
---|---|---|---|
heparin | causes dissociation to alpha1, beta1 and hence stimulation | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
phosphate | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
103000 | 109000 | phosphatase IV, gel filtration | Homo sapiens |
177000 | 180000 | phosphatase III, gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
phosphatases I, II, III, all type 2A | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
3.4 | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-80°C, 50 mM Tris-HCl buffer, pH 7.4, 1 mM EDTA, 0.5 mM dithiothreitol, 0.03 M NaCl, 10% glycerol, protease inhibitor, at least 1 month | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphohistone + H2O | - |
Homo sapiens | histone + phosphate | - |
? | |
phosphoproteins + H2O | - |
Homo sapiens | proteins + phosphate | - |
? | |
phosphorylase a + H2O | - |
Homo sapiens | phosphorylase b + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | alpha1,beta1, or AC, alpha: 32000-40000, catalytic, beta: 58000-69000, phosphatase IV | Homo sapiens |
trimer | alpha1, beta1,gamma1, phosphatase III | Homo sapiens |
trimer | alpha1,beta1,delta1, phosphatase I | Homo sapiens |