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Literature summary for 3.1.3.15 extracted from

  • Houston, L.L.; Graham, M.E.
    Divalent metal Ion effects on a mutant histidinol phophate phosphatase from Samonella typhimurium (1974), Arch. Biochem. Biophys., 162, 513-522.
    View publication on PubMed
Search for more literature for 3.1.3.15

Inhibitors

Inhibitors Comment Organism Structure
Be2+
-
 Salmonella enterica subsp. enterica serovar Typhimurium
Ca2+
-
 Salmonella enterica subsp. enterica serovar Typhimurium
Mg2+
-
 Salmonella enterica subsp. enterica serovar Typhimurium
Ni2+
-
 Salmonella enterica subsp. enterica serovar Typhimurium

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.1 0.3 L-histidinol phosphate
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Metals/Ions

Metals/Ions Comment Organism Structure
Be2+ increases Km at pH 6.5 Salmonella enterica subsp. enterica serovar Typhimurium
Co2+ shifts optimal pH to 6.5, decreases Km at pH 6.5 Salmonella enterica subsp. enterica serovar Typhimurium
Fe2+ decreases Km at pH 6.5 Salmonella enterica subsp. enterica serovar Typhimurium
Mg2+ shifts optimal pH to 6.5 Salmonella enterica subsp. enterica serovar Typhimurium
Mn2+ shifts optimal pH to 6.5, decreases Km at pH 6.5 Salmonella enterica subsp. enterica serovar Typhimurium
Ni2+ increases Km at pH 6.5 Salmonella enterica subsp. enterica serovar Typhimurium
Zn2+ shifts optimal pH to 6.5, decreases Km at pH 6.5 Salmonella enterica subsp. enterica serovar Typhimurium

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
52000
-
 disc gel electrophoresis Salmonella enterica subsp. enterica serovar Typhimurium

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-histidinol phosphate + H2O Salmonella enterica subsp. enterica serovar Typhimurium
-
 ?
-
 ?
L-histidinol phosphate + H2O Salmonella enterica subsp. enterica serovar Typhimurium TA387
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
Salmonella enterica subsp. enterica serovar Typhimurium TA387
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-histidinol phosphate + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium L-histidinol + phosphate
-
 ?
L-histidinol phosphate + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium TA387 L-histidinol + phosphate
-
 ?
L-histidinol phosphate + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
L-histidinol phosphate + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium TA387 ?
-
 ?

Subunits

Subunits Comment Organism
? x * 16000-18000, SDS-PAGE Salmonella enterica subsp. enterica serovar Typhimurium

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 in the absence of divalent metal ions Salmonella enterica subsp. enterica serovar Typhimurium