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Literature summary for 3.1.3.110 extracted from
- Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis (2008), Proc. Natl. Acad. Sci. USA, 105, 11128-11133.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) pLysS cells | Streptantibioticus cattleyicolor |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4'-phosphopantetheine + H2O | Streptantibioticus cattleyicolor | - |
pantetheine + phosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptantibioticus cattleyicolor | Q83XP6 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-NTA column chromatography | Streptantibioticus cattleyicolor |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4'-phosphopantetheine + H2O | - |
Streptantibioticus cattleyicolor | pantetheine + phosphate | - |
? | |
| additional information | the enzyme has a markedly reduced cleavage rate for prederivatized 4-phosphopantetheine | Streptantibioticus cattleyicolor | ? | - |
- |
|
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| thnH | - |
Streptantibioticus cattleyicolor |
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Release 2026.1 (March 2026)
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