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Literature summary for 3.1.3.108 extracted from

  • Nishikawa, S.; Hatanaka, Y.; Tokoro, M.; Shin, S.W.; Shimizu, N.; Nishihara, T.; Kato, R.; Takemoto, A.; Amano, T.; Anzai, M.; Kishigami, S.; Hosoi, Y.; Matsumoto, K.
    Functional analysis of nocturnin, a circadian deadenylase, at maternal-to-zygotic transition in mice (2013), J. Reprod. Dev., 59, 258-265 .
    View publication on PubMedView publication on EuropePMC
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Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Mus musculus 5737
-
nucleus
-
 Mus musculus 5634
-

Organism

Organism UniProt Comment Textmining
Mus musculus O35710
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
 Mus musculus
-
oocyte
-
 Mus musculus
-

Expression

Organism Comment Expression
Mus musculus the abundance of Nocturnin mRNA level is significantly decreased from the MII to 4-cell stages and slightly increased from the 8-cell to blastocyst stages, whereas the Nocturnin protein level is almost stable in all examined cells including GV and MII oocytes and early embryos down
Mus musculus the abundance of Nocturnin mRNA level is significantly decreased from the MII to 4-cell stages and slightly increased from the 8-cell to blastocyst stages, whereas the Nocturnin protein level is almost stable in all examined cells including GV and MII oocytes and early embryos up

General Information

General Information Comment Organism
malfunction knockdown of Nocturnin by injection of Nocturnin antisense expression vector into 1-cell embryos results in the delay of early embryonic development to the early blastocyst stage. Nocturnin-overexpressed embryos by injection of Nocturnin expression vector impair their development from the 1-cell to 2-cell or 4-cell stages Mus musculus
physiological function precise expression of nocturnin is critical to proper development of early mouse embryos. Possible role of the deadenylase at mouse maternal-to-zygotic transition Mus musculus