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Literature summary for 3.1.3.106 extracted from

  • Reddy, V.S.; Rao, D.K.; Rajasekharan, R.
    Functional characterization of lysophosphatidic acid phosphatase from Arabidopsis thaliana (2010), Biochim. Biophys. Acta, 1801, 455-461.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information incubation with phospholipids or neutral lipids has no effect on the enzyme activity Arabidopsis thaliana

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21-DE3(pLysS) cells Arabidopsis thaliana

Inhibitors

Inhibitors Comment Organism Structure
additional information the enzyme activity is insensitive to non-specific phosphatase inhibitors such as sodium o-vanadate and sodium fluoride Arabidopsis thaliana

Metals/Ions

Metals/Ions Comment Organism Structure
additional information cations like Mg2+, Mn2+, and Ca2+ have no effect on the enzyme activity Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
lysophosphatidate + H2O Arabidopsis thaliana best substrate monoacylglycerol + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography Arabidopsis thaliana

Source Tissue

Source Tissue Comment Organism Textmining
callus
-
Arabidopsis thaliana
-
leaf
-
Arabidopsis thaliana
-
root
-
Arabidopsis thaliana
-
seed
-
Arabidopsis thaliana
-
seedling
-
Arabidopsis thaliana
-
stem
-
Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-lauroyl-2-lysophosphatidate + H2O
-
Arabidopsis thaliana 1-lauroyl-sn-glycerol + phosphate
-
?
1-myristoyl-2-lysophosphatidate + H2O
-
Arabidopsis thaliana 1-myristoyl-sn-glycerol + phosphate
-
?
1-oleoyl-2-lysophosphatidate + H2O
-
Arabidopsis thaliana oleic acid + sn-glycerol 3-phosphate
-
?
1-palmitoyl-2-lysophosphatidate + H2O
-
Arabidopsis thaliana 1-palmitoyl-sn-glycerol + phosphate
-
?
1-stearoyl-2-lysophosphatidate + H2O
-
Arabidopsis thaliana 1-stearoyl-sn-glycerol + phosphate
-
?
lysophosphatidate + H2O best substrate Arabidopsis thaliana monoacylglycerol + phosphate
-
?
additional information the purified recombinant enzyme does not hydrolyze sphingosine 1-phosphate, diacylglycerol diphosphate, glycerol-3-phosphate, lysophosphatidylcholine, lysophosphatidylethanolamine and phosphatidate Arabidopsis thaliana ?
-
?

Synonyms

Synonyms Comment Organism
At3g03520
-
Arabidopsis thaliana
LPA phosphatase
-
Arabidopsis thaliana
lysophosphatidic acid phosphatase
-
Arabidopsis thaliana

Expression

Organism Comment Expression
Arabidopsis thaliana lysophosphatidic acid phosphatase is highly expressed during phosphate starvation, cab leaf virus infection, and abiotic stresses (heat, syringolin, bamacia tabaci) up

General Information

General Information Comment Organism
physiological function lysophosphatidate phosphatase plays a significant role in supplying the phosphate during phosphate-deficient conditions Arabidopsis thaliana