Literature summary for 3.1.3.1 extracted from

Trevino, S.; Andrade-Garcia, A.; Herrera Camacho, I.; Leon-Chavez, B.; Aguilar-Alonso, P.; Flores, G.; Brambila, E.
Chronic cadmium exposure lead to inhibition of serum and hepatic alkaline phosphatase activity in Wistar rats (2015), J. Biochem. Mol. Toxicol., 29, 587-594 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
Cd2+	chronic cadmium exposure (32.5 ppm Cd2+ in purified water over 3 months) leads to noncompetitive inhibition of serum and hepatic enzyme activity. The addition of 5 mM of Zn2+ shows almost 58% reactivation of the enzyme	Rattus norvegicus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	required	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-
serum	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-nitrophenyl phosphate + H2O	-	Rattus norvegicus	4-nitrophenol + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
ALP	-	Rattus norvegicus

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Release 2023.1 (January 2023)