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Literature summary for 3.1.26.7 extracted from

  • Schmitz, M.; Tinoco, I.Jr.
    Solution structure and metal-ion binding of the P4 element from bacterial RNase P RNA (2000), RNA, 6, 1212-1225.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information construction of a mutant enzymatically active enzyme P4 RNA ribozyme with altered metal ion specificity, preference for Ca2+ instead of Mg2+ Escherichia coli

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information kinetics and thermodynamics of RNA binding by wild-type and mutant ribozymes Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ preferred by mutant ribozyme, binding structure of the enzyme RNA P4 element, affinities of wild-type and mutant P4 element Escherichia coli
Mg2+ preferred by wild-type ribozyme, binding structure of the enzyme RNA P4 element, affinities of wild-type and mutant P4 element Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
functionally active enzyme RNA P4 element ribozyme
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
RNA + H2O from Escherichia coli and Methylophilus methylotrophus Escherichia coli ?
-
?

Subunits

Subunits Comment Organism
More structural model of functionally active enzyme RNA P4 element ribozyme, metal ions binding structure, hairpin structure complexed with Mg2+, Ca2+, or cobalt(III)-hexamine, wild-type and mutant ribozymes, overview Escherichia coli

Synonyms

Synonyms Comment Organism
P4
-
Escherichia coli
RNase P
-
Escherichia coli
RNase P RNA
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Escherichia coli