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Literature summary for 3.1.26.4 extracted from
- Differential role of the protein matrix on the binding of a catalytic aspartate to Mg2+ vs Ca2+: application to ribonuclease H (2013), J. Am. Chem. Soc., 135, 6541-6548.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Escherichia coli |  |
| Ca2+ | - |
Moloney murine leukemia virus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | native cofactor | Moloney murine leukemia virus | |
| Mg2+ | native cofactor | Escherichia coli | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| RNA-DNA hybrid + H2O | Moloney murine leukemia virus | - |
ribonucleotide 5'-phosphomonoester + ? | - |
? | |
| RNA-DNA hybrid + H2O | Escherichia coli | - |
ribonucleotide 5'-phosphomonoester + ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | P0A7Y4 | - |
- |
| Moloney murine leukemia virus | P03355 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| RNA-DNA hybrid + H2O | - |
Moloney murine leukemia virus | ribonucleotide 5'-phosphomonoester + ? | - |
? | |
| RNA-DNA hybrid + H2O | - |
Escherichia coli | ribonucleotide 5'-phosphomonoester + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| RNase H | - |
Moloney murine leukemia virus |
| RNase H | - |
Escherichia coli |
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