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Literature summary for 3.1.26.3 extracted from

  • Chevalier, C.; Huntzinger, E.; Fechter, P.; Boisset, S.; Vandenesch, F.; Romby, P.; Geissmann, T.
    Staphylococcus aureus endoribonuclease III purification and properties (2008), Methods Enzymol., 447, 309-327.
    View publication on PubMed
Search for more literature for 3.1.26.3

Cloned(Commentary)

Cloned (Comment) Organism
overexpressed in Escherichia coli Staphylococcus aureus

Protein Variants

Protein Variants Comment Organism
additional information rnc mutant (obtained by homologous recombination) is viable. Deletion of the rnc gene in Staphylococcus aureus does not affect cell growth in rich medium Staphylococcus aureus

Inhibitors

Inhibitors Comment Organism Structure
Ca2+ recombinant Sa-RNase III is inhibited by Ca2+ Staphylococcus aureus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ recombinant Sa-RNase III requires MgCl2 for activity Staphylococcus aureus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
27900
-
 homodimer of 243 amino acid polypeptides Staphylococcus aureus

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Staphylococcus aureus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dsRNA + H2O process double-stranded RNAs consisting of two turns of the RNA helix. Although the enzyme plays a role in ribosomal RNA processing and gene regulation, enzyme is not essential for cell growth but regulates virulence gene expression Staphylococcus aureus mature RNA
-
 ?

Subunits

Subunits Comment Organism
homodimer
-
 Staphylococcus aureus

Synonyms

Synonyms Comment Organism
endoribonuclease III
-
 Staphylococcus aureus
Sa-RNase III
-
 Staphylococcus aureus