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Literature summary for 3.1.26.12 extracted from
- Ribonuclease E organizes the protein interactions in the Escherichia coli RNA degradosome (1998), Genes Dev., 12, 2770-2781.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| overexpression of wild-type and truncation mutant enzymes in strain Bl21(DE3), expression in the yeast two-hybrid system, overview | Escherichia coli |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | functional analysis of enzyme domains by using deletion mutants of RNase E, interaction with degradosome components, overview | Escherichia coli |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| additional information | the enzyme is part of the RNA degradosome, a large multiprotein machine to process and degrade RNA | Escherichia coli | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Escherichia coli | the enzyme is part of the RNA degradosome, a large multiprotein machine to process and degrade RNA | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
gene rne, strain XA103 and PB4144 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme is part of the RNA degradosome, a large multiprotein machine to process and degrade RNA | Escherichia coli | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | the enzyme is part of the RNA degradosome, a large multiprotein machine to process and degrade RNA, organization, overview, the enzymes' C-terminal half contains the binding sites for the three other degradosome protein components DEAD-box RNA helicase RhlB, enolase, and polynucleotide phosphorylase PNPase, the C-terminal half of RNase E acts as a scaffold upon which the other components of the complex are assembled, functional analysis of enzyme domains by using deletion mutants of RNase E, overview | Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ribonuclease E | - |
Escherichia coli |
| RNase E | - |
Escherichia coli |
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