Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
central nervous system | predominant expression during the third larval instar | Drosophila melanogaster | - |
fat body | - |
Drosophila melanogaster | - |
gonad | - |
Drosophila melanogaster | - |
gut | - |
Drosophila melanogaster | - |
larva | - |
Drosophila melanogaster | - |
prepupa | - |
Drosophila melanogaster | - |
salivary gland | - |
Drosophila melanogaster | - |
testis | - |
Drosophila melanogaster | - |
Synonyms | Comment | Organism |
---|---|---|
RNase ZL | - |
Drosophila melanogaster |
RNaseZ | - |
Drosophila melanogaster |
General Information | Comment | Organism |
---|---|---|
malfunction | RNZED24 knockout mutation causes early larval lethality. RNaseZ knockout completely blocks tRNA maturation without diminishing the abundance of mature tRNA molecules, affects the nuclear-cytoplasmic distribution of tRNA, decreases cell proliferation but not cell survival, and affects maginal disc growth autonomously | Drosophila melanogaster |
physiological function | RNase Z activity is essential for all phases of fly development that involve cell division, including growth of adult tissue progenitors during larval and metamorphic stages, and gametogenesis in adults | Drosophila melanogaster |