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Literature summary for 3.1.26.11 extracted from

  • Gan, X.; Yang, J.; Li, J.; Yu, H.; Dai, H.; Liu, J.; Huang, Y.
    The fission yeast Schizosaccharomyces pombe has two distinct tRNase ZLs encoded by two different genes and differentially targeted to the nucleus and mitochondria (2011), Biochem. J., 435, 103-111.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
functional expression of isozymes in Schizosaccharomyces pombe cells Schizosaccharomyces pombe

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion isozyme SpTrz2p, is a mitochondrial protein with an N-terminal MTS,mitochondrial-targeting signal Schizosaccharomyces pombe 5739
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nucleus isozyme SpTrz1p, localizes to the nucleus and has a simian virus 40 nuclear localization signal-like structure at its N-terminus, which contains four consecutive arginine and lysine residues between residues 208 and 211 that are critical for the NLS function Schizosaccharomyces pombe 5634
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Organism

Organism UniProt Comment Textmining
Schizosaccharomyces pombe
-
genes sptrz1+ and sptrz2+, isozymes SpTrz1p and SpTrz2p
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pre-tRNAArg + H2O
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Schizosaccharomyces pombe tRNAArg + 3'-leader of tRNA
-
?

Synonyms

Synonyms Comment Organism
SpTrz1p
-
Schizosaccharomyces pombe
SpTrz2p
-
Schizosaccharomyces pombe
tRNase ZL
-
Schizosaccharomyces pombe

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
assay at Schizosaccharomyces pombe

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
assay at Schizosaccharomyces pombe

General Information

General Information Comment Organism
additional information Schizosaccharomyces pombe contains two candidate tRNase ZLs encoded by the essential genes sptrz1+ and sptrz2+ Schizosaccharomyces pombe