Cloned (Comment) | Organism |
---|---|
293 and HeLa cells co-transfected with the tRNase ZL expression plasmid (+ZL), the tRNase ZS expression plasmid (+ZS), the tRNase ZL siRNA (-ZL), or the Ago2 siRNAs | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
long form of tRNase Z | - |
Homo sapiens |
tRNase ZL | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | cytosolic tRNase ZL modulates gene expression through a subset of microRNAs in the cells. MiR-103 can form a hook structure to guide target RNA cleavage by cytosolic tRNase ZL in vitro. MiR-103 downregulates gene expression through directing mRNA cleavage by tRNase ZL | Homo sapiens |