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Literature summary for 3.1.26.11 extracted from

  • Spaeth, B.; Canino, G.; Marchfelder, A.
    tRNase Z: the end is not in sight (2007), Cell. Mol. Life Sci., 64, 2404-2412.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information variants of tRNase Z enzymes generated by mutagenesis and properties of variants reviewed Arabidopsis thaliana

Metals/Ions

Metals/Ions Comment Organism Structure
additional information overview of the metal ion content in the active sites of tRNase Z and metallo-beta-lactamases, metal ion requirement by cleavage of bis(p-nitrophenyl)phosphate indicated, structure of metal binding site described, key residues of the zinc site identified by mutational studies summarized Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
features of tRNase Z reviewed
-
Caenorhabditis elegans
-
distribution of short and long forms of tRNase Z reviewed
-
Danio rerio
-
distribution of short and long forms of tRNase Z reviewed
-
Drosophila melanogaster Q8MKW7 distribution of short and long forms of tRNase Z reviewed
-
Gallus gallus
-
distribution of short and long forms of tRNase Z reviewed
-
Homo sapiens
-
distribution of short and long forms of tRNase Z reviewed
-
Mus musculus
-
distribution of short and long forms of tRNase Z reviewed
-
Neurospora crassa
-
distribution of short and long forms of tRNase Z reviewed
-
Saccharomyces cerevisiae
-
distribution of short and long forms of tRNase Z reviewed
-
Schizosaccharomyces pombe
-
distribution of short and long forms of tRNase Z reviewed
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
in vitro processing activities of different recombinant tRNase Z enzymes with respect to CCA-containing and CCA-less pre-tRNAs summarized Arabidopsis thaliana

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
bis(p-nitrophenyl)phosphate + H2O differentiation of tRNase Z variants by the substrate bis(p-nitrophenyl)phosphate (bpNPP) described, smallest known tRNase Z substrate Arabidopsis thaliana p-nitrophenol + p-nitrophenyl phosphate
-
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Synonyms

Synonyms Comment Organism
tRNase Z
-
Gallus gallus
tRNase Z
-
Mus musculus
tRNase Z
-
Homo sapiens
tRNase Z
-
Saccharomyces cerevisiae
tRNase Z
-
Neurospora crassa
tRNase Z
-
Arabidopsis thaliana
tRNase Z
-
Schizosaccharomyces pombe
tRNase Z
-
Caenorhabditis elegans
tRNase Z
-
Danio rerio
tRNase Z
-
Drosophila melanogaster
Trz
-
Gallus gallus
Trz
-
Mus musculus
Trz
-
Homo sapiens
Trz
-
Saccharomyces cerevisiae
Trz
-
Neurospora crassa
Trz
-
Arabidopsis thaliana
Trz
-
Schizosaccharomyces pombe
Trz
-
Caenorhabditis elegans
Trz
-
Danio rerio
Trz
-
Drosophila melanogaster