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BRENDA support

Literature summary for 3.1.22.1 extracted from

  • Yu, H.; Lai, H.J.; Lin, T.W.; Chen, C.S.; Lo, S.J.
    Loss of DNase II function in the gonad is associated with a higher expression of antimicrobial genes in Caenorhabditis elegans (2015), Biochem. J., 470, 145-154 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans P34387
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Caenorhabditis elegans Q17778
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Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
crn-7
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Caenorhabditis elegans
Nuc-1
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Caenorhabditis elegans

General Information

General Information Comment Organism
malfunction loss of CRN-7 leads to up-regulation of antimicrobial genes Caenorhabditis elegans
malfunction loss of NUC-1 leads to up-regulation of antimicrobial genes Caenorhabditis elegans
physiological function the enzyme plays a role in degrading apoptotic DNA in distinct sites of the gonad, and acts as negative regulators of innate immunity Caenorhabditis elegans