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Literature summary for 3.1.22.1 extracted from
- DNase IIbeta distribution and activity in the mouse lens (2007), Invest. Ophthalmol. Vis. Sci., 48, 5638-5646.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | during early differentiation, localization to lysosome. Later, an increasing portion of enzyme is found in cytosol | Mus musculus | 5829 | - |
| lysosome | during early differentiation | Mus musculus | 5764 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fiber | isoform DNase IIbeta accounts for about 50% of the acid nuclease activity in cortical fiber cell. Activity is strongest in early differentiation and associated with the lysosomal fraction. Later, an increasing portion of enzyme is found in cytosol | Mus musculus | - |
| lens | - |
Mus musculus | - |
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