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Literature summary for 3.1.21.7 extracted from

  • McCullough, A.K.; Schärer, O.; Verdine, G.L.; Lloyd, R.S.
    Structural determinants for specific recognition by T4 endonuclease V (1996), J. Biol. Chem., 271, 32147-32152.
    View publication on PubMed
Search for more literature for 3.1.21.7

Cloned(Commentary)

Cloned (Comment) Organism
-
 Tequatrovirus T4

Protein Variants

Protein Variants Comment Organism
E23D altered affinities for pyrrolidine- and tetrahydrofuran-residues or reduced apurinic sites Tequatrovirus T4
E23Q altered affinities for a pyrrolidine- and tetrahydrofuran residues or reduced apurinic sites Tequatrovirus T4

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA + H2O Tequatrovirus T4 pyrimidine dimer-specific 5'-phosphoryltermini DNA + 3'-hydroxyltermini DNA
-
 ?

Organism

Organism UniProt Comment Textmining
Tequatrovirus T4
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Tequatrovirus T4

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
49-mer oligonucleotide + H2O also possesses abasic lyase activity Tequatrovirus T4 hydrolysed DNA
-
 ?
49-mer oligonucleotide + H2O double-stranded, containing a site-specific duplex cis-syn cyclobutane pyrimidine dimer Tequatrovirus T4 hydrolysed DNA
-
 ?
DNA + H2O pyrimidine dimer-specific Tequatrovirus T4 5'-phosphoryltermini DNA + 3'-hydroxyltermini DNA
-
 ?

Synonyms

Synonyms Comment Organism
T4 endonuclease V
-
 Tequatrovirus T4