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Literature summary for 3.1.21.6 extracted from

  • Xia, Y.; Morgan, R.; Schildkraut, I.; van Etten, J.L.
    A site-specific single strand endonuclease activity induced by NYs-1 virus infection of a Chlorella-like green alga (1988), Nucleic Acids Res., 16, 9477-9487.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Virus NYs-1
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dsDNA-containing virus
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Source Tissue

Source Tissue Comment Organism Textmining
additional information Chlorella sp. strain NC64A cell infected with the dsDNA-containing virus NYs-1 Virus NYs-1
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
double-stranded DNA the enzyme recognizes the sequence 5'-CC-3' and cleaves 5' to the first C. It cleaves 5'-CIIIC-3' sequences but not 5'-IIICC-3' sequences. The enzyme creates breaks in dsDNA whenever two 5-CC-3' sequences on opposite strands are close enough for the two strands to separate. When the 5'-CC-3' sequence on opposite strands are further apart only a portion of the strands separate Virus NYs-1 ?
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additional information the enzyme does not cleave ssDNA and definitely does not cleave ssRNA or dsRNA Virus NYs-1 ?
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