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Literature summary for 3.1.21.5 extracted from

  • Meisel, A.; Mackeldanz, P.; Bickle, T.A.; Kruger, D.H.; Schroeder, C.
    Type III restriction endonucleases translocate DNA in a reaction driven by recognition site-specific ATP hydrolysis (1995), EMBO J., 14, 2958-2966.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Escherichia coli
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enzyme EcoP15I
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA + H2O restriction requires a pair of unmethylated, inversely oriented recognition sites. Suicidal restriction by EcoP15I is prevented if all the unmodified sites are in the same orientation. EcoP15I possesses an intrisic ATPase activity, the potential driving force of DNA translocation. The ATPase is recognition site-specific Escherichia coli specific double-stranded DNA fragments with terminal 5'-phosphate
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Synonyms

Synonyms Comment Organism
EcoP15I
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Escherichia coli