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Literature summary for 3.1.21.3 extracted from

  • Waldron, D.E.; Lindsay, J.A.
    Sau1: a novel lineage-specific type I restriction-modification system that blocks horizontal gene transfer into Staphylococcus aureus and between S. aureus isolates of different lineages (2006), J. Bacteriol., 188, 5578-5585.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.21.3

Protein Variants

Protein Variants Comment Organism
additional information gene of subunit hsdR from strain RN4220 contains a premature stop codon resulting in a truncated R.Sau1 product of 192 amino acids. Strain RN4220 can accept plasmid DNA from Escherichia coli. The truncated hsdR subunit is responsible for this phenotype and its complementation restores a nontransformable phenotype. Complemented strain RN4220 is resisitant to bacteriophage lysis if the phage is grown on staphylococcus aureus of a different lineage Staphylococcus aureus

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Staphylococcus aureus isoform Sau1 is the major mechanism for blocking transfer of resistance genes and other mobile genetic elements into Staphylococcus aureus isolates from other species, as well as for controlling the spread of resistance genes between isolates of different Staphylococcus aureus lineages ?
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 ?

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus
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 strain RN4220 can accept plasmid DNA from Escherichia coli. A mutation in hsdR subunit of isoform Sau1 is responsible for this phenotype and its complementation restores a nontransformable phenotype. Complemented strain RN4220 is resistant to bacteriophage lysis if the phage is grown on staphylococcus aureus of a different lineage
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information isoform Sau1 is the major mechanism for blocking transfer of resistance genes and other mobile genetic elements into Staphylococcus aureus isolates from other species, as well as for controlling the spread of resistance genes between isolates of different Staphylococcus aureus lineages Staphylococcus aureus ?
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 ?

Synonyms

Synonyms Comment Organism
Sau1
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 Staphylococcus aureus