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Literature summary for 3.1.21.1 extracted from

  • Ts Mavrova, A.; Dimov, S.; Yancheva, D.; Kolarevic, A.; Ilic, B.S.; Kocic, G.; Smelcerovic, A.
    Synthesis and DNase I inhibitory properties of some 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines (2018), Bioorg. Chem., 80, 693-705 .
    View publication on PubMed
Search for more literature for 3.1.21.1

Inhibitors

Inhibitors Comment Organism Structure
2-(2-(4-nitrobenzyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)isoindoline-1,3-dione
-
 Bos taurus
2-(2-(pyridin-2-yl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)isoindoline-1,3-dione
-
 Bos taurus
2-(2-ethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)isoindoline-1,3-dione
-
 Bos taurus
2-(3-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine
-
 Bos taurus
2-(4-nitrobenzyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine
-
 Bos taurus
2-(pyridin-2-yl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine
-
 Bos taurus
2-benzyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine
-
 Bos taurus
2-ethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine
-
 Bos taurus
Crystal violet
-
 Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus P00639
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
 Bos taurus
-

Synonyms

Synonyms Comment Organism
DNase I
-
 Bos taurus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.106
-
 pH and temperature not specified in the publication Bos taurus 2-(2-(4-nitrobenzyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)isoindoline-1,3-dione
0.128
-
 pH and temperature not specified in the publication Bos taurus 2-(4-nitrobenzyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine
0.134
-
 pH and temperature not specified in the publication Bos taurus 2-(2-(pyridin-2-yl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)isoindoline-1,3-dione
0.148
-
 pH and temperature not specified in the publication Bos taurus 2-(3-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine
0.148
-
 pH and temperature not specified in the publication Bos taurus 2-(2-ethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)isoindoline-1,3-dione
0.156
-
 pH and temperature not specified in the publication Bos taurus 2-(pyridin-2-yl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine
0.195
-
 pH and temperature not specified in the publication Bos taurus 2-ethyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine
0.197
-
 pH and temperature not specified in the publication Bos taurus 2-benzyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-amine