Application | Comment | Organism |
---|---|---|
medicine | patients with type 2 diabetes show a significant elevation of DNase I activity in serum, and increase in DNase I expression is observed in the pancreas of diabetic persons | Homo sapiens |
medicine | rats with diabetes induced by streptozotocin injection and high fat diet show a significant elevation of DNase I activity in serum, and increase in DNase I expression is observed in the pancreas of diabetic rats. High glucose induces both DNase I and caspase-3 expression and at the same time increases apoptosis rate of INS-1 cells | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
pancreas | - |
Rattus norvegicus | - |
serum | - |
Homo sapiens | - |
serum | - |
Rattus norvegicus | - |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | high glucose induces both DNase I and caspase-3 | up |