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Literature summary for 3.1.21.1 extracted from

  • Lichtinghagen, R.
    Determination of Pulmozyme (dornase alpha) stability using a kinetic colorimetric DNase I activity assay (2006), Eur. J. Pharm. Biopharm., 63, 365-368.
    View publication on PubMed

Application

Application Comment Organism
analysis enzymatic activity assay for determination of enzyme stability. Method bases on a colorimetric endpoint activity assay using degradation of a DNA/methyl green complex and is feasible on an automated analyzer system within a rather short time Homo sapiens
medicine enzymatic activity assay for determination of enzyme stability. Method bases on a colorimetric endpoint activity assay using degradation of a DNA/methyl green complex and is feasible on an automated analyzer system within a rather short time. Application of method proves the reliability of enzyme during aerosolization with inhalation devices Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
dornase alpha, recombinant enzyme
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
enzymatic activity assay for determination of enzyme stability. Method bases on a colorimetric endpoint activity assay using degradation of a DNA/methyl green complex and is feasible on an automated analyzer system within a rather short time Homo sapiens

Synonyms

Synonyms Comment Organism
dornase alpha
-
Homo sapiens