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Literature summary for 3.1.21.1 extracted from

  • Yasuda, T.; Takeshita, H.; Ueki, M.; Iida, R.; Nakajima, T.; Mori, S.; Mogi, K.; Kaneko, Y.; Kishi, K.
    Tissue-specific in vivo inhibition of DNase I gene expression by somatostatin (2001), Biochem. Biophys. Res. Commun., 283, 287-291.
    View publication on PubMed
Search for more literature for 3.1.21.1

Cloned(Commentary)

Cloned (Comment) Organism
quantification of gene transcript in somatostatin treated animals Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
EGTA complete inhibition of the enzyme from serum at 5 mM Rattus norvegicus
Somatostatin 2 enzyme forms: a somatostatin-sensitive and a somatostatin-resistant, controls the enzyme level in the lower gut, in vivo transient down-regulation of gene expression of the sensitive enzyme form Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular serum Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P21704 Sprague-Dawley rats
-

Source Tissue

Source Tissue Comment Organism Textmining
hindgut somatostatin-sensitive enzyme form Rattus norvegicus
-
ileum somatostatin-sensitive enzyme form Rattus norvegicus
-
kidney somatostatin-resistant enzyme form Rattus norvegicus
-
liver somatostatin-resistant enzyme form Rattus norvegicus
-
parotid gland somatostatin-resistant enzyme form Rattus norvegicus
-
pituitary gland somatostatin-sensitive enzyme form Rattus norvegicus
-
serum somatostatin-sensitive enzyme form Rattus norvegicus
-
small intestine somatostatin-sensitive enzyme form Rattus norvegicus
-
stomach somatostatin-sensitive enzyme form Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA + H2O
-
 Rattus norvegicus 5'-phosphodinucleotide + 5'-phosphooligonucleotide
-
 ?

Synonyms

Synonyms Comment Organism
DNase I
-
 Rattus norvegicus